Medipyxis
blog7 min read

Wound Care CPT Cheat Sheet 2026: Quick Reference for Mobile Clinicians

The one-page wound care CPT cheat sheet — every code you bill, organized by visit type, with modifiers, documentation triggers, and Medicare reimbursement ranges.

D

Damon Ebanks

Medipyxis

Wound Care CPT Cheat Sheet 2026: Quick Reference for Mobile Clinicians

Wound Care CPT Cheat Sheet 2026: Quick Reference for Mobile Clinicians

This is the printable quick-reference version of our complete wound care CPT code guide. Every code is organized by visit type with Medicare POS 12 (home) reimbursement ranges, documentation triggers, and the modifiers that prevent denials. Bookmark it, print it, keep it in your bag.


Table 1: E/M Codes (Office/Outpatient Visits)

Bill with modifier -25 when performed on the same day as a procedure. MDM level determines the code — not time, unless time-based billing is elected.

CodeDescriptionMDM LevelKey MDM CriteriaMedicare POS 12
99213Established patient, low MDMLow2+ self-limited problems; minimal data review; low risk of complications~$75-$92
99214Established patient, moderate MDMModerate1+ chronic illness with exacerbation, or 2+ stable chronic conditions; moderate data review; Rx drug management~$110-$130
99215Established patient, high MDMHigh1+ chronic illness with severe exacerbation, or acute illness posing threat to life/function; extensive data review; high-risk decisions~$155-$175

Most wound care visits land at 99214. A straightforward wound check with no change in plan is 99213. A wound with new infection, treatment plan overhaul, or multiple comorbidities affecting healing supports 99215.


Table 2: Debridement Codes

Two distinct families: selective (nonviable tissue only) and excisional (cutting into viable tissue with active bleeding). The clinical distinction drives the code — see the debridement billing guide for full documentation rules.

Selective Debridement

CodeDescriptionSizeMedicare POS 12
97597Selective debridement, first woundFirst 20 sq cm or less~$80-$90
97598Selective debridement, add-onEach additional 20 sq cm~$30-$40

Excisional Debridement (by deepest tissue layer)

CodeDescriptionDepthSizeMedicare POS 12
11042Excisional debridementSkin/subcutaneousFirst 20 sq cm~$130-$150
11043Excisional debridementMuscle/fasciaFirst 20 sq cm~$235-$255
11044Excisional debridementBoneFirst 20 sq cm~$340-$360
11045Add-on to 11042Skin/subcutaneousEach addl 20 sq cm~$45-$55
11046Add-on to 11043Muscle/fasciaEach addl 20 sq cm~$70-$80
11047Add-on to 11044BoneEach addl 20 sq cm~$90-$105

Code to the deepest tissue layer removed. Add-ons must match their primary (11045 pairs only with 11042, etc.).


Table 3: Skin Substitute Application

Codes split by anatomical site: trunk/arms/legs vs. face/scalp/eyelids/hands/feet/genitalia. First code is the primary; second is the add-on for additional area.

CodeDescriptionSiteSizeMedicare POS 12
15271Skin substitute graft, firstTrunk, arms, legsFirst 25 sq cm~$117 application + $127.14/sq cm product-$400
15272Add-on to 15271Trunk, arms, legsEach addl 25 sq cm~$60-$80
15275Skin substitute graft, firstFace, scalp, hands, feet, genitaliaFirst 25 sq cm~$117 application + $127.14/sq cm product-$420
15276Add-on to 15275Face, scalp, hands, feet, genitaliaEach addl 25 sq cm~$65-$85

Measure graft size applied, not wound size. Document product name, lot number, and wound bed preparation. See our skin substitute billing guide for LCD requirements.


Table 4: Negative Pressure Wound Therapy (NPWT)

CodeDescriptionIndicationMedicare POS 12
97607NPWT, wound surface area up to 50 sq cmWound area 50 sq cm or less per session~$80-$100
97608NPWT, wound surface area > 50 sq cmWound area exceeding 50 sq cm per session~$115-$135

These are per-session codes. Document wound size at each visit. NPWT must be medically necessary with documented wound bed preparation and progress notes supporting continued use.


Table 5: Compression Therapy

CodeDescriptionProcedureMedicare POS 12
29580Strapping, Unna bootApplication of Unna boot zinc paste bandage~$55-$70
29581Multi-layer compressionApplication of multi-layer venous wound compression system (e.g., Profore, Coban 2)~$65-$80

Compression is separately billable from debridement and E/M. Document the type of system applied, number of layers, and the clinical indication (typically venous insufficiency with ICD-10 I87.2 or active venous ulcer L97.x).


Table 6: Common Modifiers

ModifierNameWhen to UseExample
-25Significant, separately identifiable E/ME/M performed on same day as a procedure; the E/M must reflect decision-making beyond what's inherent to the procedure99214-25 + 97597 on same visit
-59Distinct procedural serviceTwo procedures that normally bundle, performed on separate wounds or anatomical sites97597 on left leg wound + 97597-59 on right leg wound
-76Repeat procedure, same physicianSame procedure repeated on a different wound during the same sessionSecond debridement on a separate wound same visit
-79Unrelated procedure during postoperative periodProcedure unrelated to the original surgery during its global periodNew wound debridement during post-op period of a prior skin graft
KXRequirements metCertifies that LCD/NCD coverage criteria have been met; required by some MACs for skin substitutes and NPWTKX appended when LCD medical necessity documentation is complete

Full modifier rules with documentation examples in the modifier guide.


Table 7: Common Wound Care ICD-10 Codes

CodeDescriptionTypical Use
L97.119Non-pressure ulcer of right thigh, unspecified severityVenous/arterial leg ulcers by location
L97.519Non-pressure ulcer of other part of right foot, unspecified severityFoot ulcers (non-diabetic)
L97.929Non-pressure ulcer of unspecified part of left lower leg, unspecified severityLower extremity ulcers, general
L89.150Pressure ulcer of sacral region, unstageableSacral pressure injuries
L89.310Pressure ulcer of right buttock, stage 1Pressure injuries by stage (1-4)
E11.621Type 2 diabetes with foot ulcerDiabetic foot ulcer (pair with L97.x for site)
E11.622Type 2 diabetes with other skin ulcerDiabetic skin ulcer, non-foot
I87.2Venous insufficiency (chronic/peripheral)Underlying cause for venous leg ulcers
L03.115Cellulitis of right lower limbWound infection/cellulitis
T81.31XADisruption of external operation wound, initial encounterSurgical wound dehiscence

Code to the highest specificity available. Laterality (left/right), anatomical site, severity, and stage all affect code selection. Use E11.621 + L97.x together for diabetic foot ulcers — the diabetes code alone is insufficient. Pressure ulcers require staging (L89.x10 through L89.x14 for stages 1-4).


Reimbursement ranges shown are 2026 Medicare Physician Fee Schedule national averages for POS 12 (home). Actual rates vary by MAC jurisdiction, geographic locality, and payer contract. Verify current rates with your MAC or payer fee schedule.

Want to learn more about Medipyxis?

Explore how mobile wound care practices use Medipyxis to reduce denials and capture more referrals.